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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
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DOTAP chloride (GMP Like) is a GMP Like class of DOTAP chloride that serves as an auxiliary reagent for cell therapy manufacture. It is a cationic lipid known for its good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can function as an excipient for transient and stable transfection of DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without requiring a helper lipid.
Gmp like class DOTAP chloride
Auxiliary reagent for cell therapy manufacture
Cationic lipid
Good membrane fusion ability
Biocompatibility
Can be used as an excipient for transient and stable transfection of DNA and modified nucleic acids without helper lipid
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Butyryl-L-carnitine chloride is an acylcarnitine research reagent used as a reference standard in metabolic, analytical, and pharmacological studies. It is supplied as a white to off-white solid with high reported purity.
White to off-white solid, easily handled in laboratory settings.
Reported purity 98.1% (manufacturer listing).
CAS number 162067-50-7 for unambiguous identification.
Chemical formula C11H22ClNO4 and molecular weight 267.75 g/mol.
Suitable as a reference standard for metabolic and analytical assays.
Available in small research sizes for analytical use.
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Rocuronium Bromide (CAS 119302-91-9) is an aminosteroid compound that functions as a non-depolarizing neuromuscular blocking agent It acts by competitively antagonizing nicotinic acetylcholine receptors at the neuromuscular junction thereby inhibiting acetylcholine-induced depolarization and subsequent muscle contraction In research settings Rocuronium Bromide is utilized to investigate neuromuscular transmission and to model pharmacological blockade of skeletal muscle activity supporting studies in anesthesia muscle physiology and synaptic transmission mechanisms
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4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a heterocyclic compound featuring a five-membered ring structure. It serves as a versatile compound in scientific research.
Can be used as a starting material for organic synthesis.
Functions as a reagent for organic transformation.
Acts as a biological probe for studying biological processes.
Utilized as a biomaterial or organic compound for life sciences research.
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2 4-Pyridinedicarboxylic acid (Lutidinic Acid 2 4-Dicarboxypyridine 2 4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG) and chelates zinc thus affecting a range of enzymes It blocks the activity of 2-OG oxygenases
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